| University São Paulo (USP),Brazil | BRAZIL

Dr. Isabel Maciel is a biomedical and medical mycology researcher with professional experience in laboratory science, invasive fungal diseases, immunology, and infectious disease diagnostics, In addition to her scientific activities, Dr. Maciel has professional experience as a Technical Responsible (RT) at Trusty Surgical. Her professional activities reflect expertise in technical responsibility, laboratory practices, surgical materials, and healthcare-related scientific work.

Research & Scientific Contributions

Dr. Maciel has contributed to research in medical mycology, fungal infections, immunology, and diagnostic investigation. Her published research includes studies on factors affecting the production of Histoplasma capsulatum antigens and evaluation of immune responses following stimulation with Cryptococcus neoformans and Cryptococcus gattii antigens among individuals frequently exposed to these fungi.

Her research interests extend to invasive fungal infections, cryptococcosis, fungal antigen production, host immune responses, T-cell populations, antifungal activity, and laboratory-based diagnosis. Her work demonstrates an interdisciplinary approach combining microbiology, immunology, mycology, and clinical research.

Publications & Scholarly Output

Dr. Maciel has authored and co-authored peer-reviewed research articles, including publications in the Revista do Instituto Adolfo Lutz and the Journal de Mycologie Médicale. Her 2022 publication investigating IFN-γ responses to C. neoformans and C. gattii antigens was indexed in Scopus.

She has also contributed as a book author/co-author to the 2025 IntechOpen publication “Invasive Fungal Diseases Caused by Fungi of the Genera Aspergillus and Fusarium and Agents of the Order Mucorales,” demonstrating her contribution to contemporary scientific literature on invasive mycoses.

Conference Presentations & Scientific Engagement

Dr. Maciel has actively presented scientific work at conferences, including research on the antifungal activity of fluconazole in combination with tacrolimus and cyclosporine A against Trichophyton isolates from patients with renal disease. She has also presented research involving flow-cytometric analysis of CD3+/CD4+ T-cell populations and CD4+CD45RA naïve and memory T cells in immunocompetent patients with neurocryptococcosis.

Training & Professional Development

Her professional development includes participation in scientific congresses, workshops, meetings, and specialized training in areas such as molecular methodologies for epidemiology and diagnosis of invasive fungal infections, biosafety and good laboratory practices, cryptococcosis, flow cytometry, molecular biology in infectious disease diagnosis, primary immunodeficiencies, autoinflammatory diseases, and immunological responses.

Her participation in specialized scientific programs from 2007 onward demonstrates sustained engagement with advances in biomedical research and laboratory medicine.

Research Impact & Scientific Profile

Dr. Isabel Maciel's scientific profile is characterized by continued involvement in medical mycology and infectious disease research, with particular emphasis on fungal pathogens, invasive mycoses, immunological responses, antifungal investigations, and diagnostic methodologies. Her combination of research publications, book contributions, conference presentations, specialized training, and professional technical responsibility reflects a dedicated commitment to scientific and healthcare advancement.

Eligibility for Most Determined Researcher Award 

Dr. Isabel Maciel is eligible for the Most Determined Researcher Award in Scientific Laurels in recognition of her sustained dedication to biomedical and medical mycology research. Her peer-reviewed publications, contribution to a scientific book, conference presentations, specialized training, and continued professional engagement in fungal disease research demonstrate determination toward advancing knowledge in medical mycology, immunology, infectious diseases, and laboratory diagnostics. Her consistent scientific participation and multidisciplinary research contributions make her a deserving candidate for this recognition.